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Filtered Search Results
Cayman Chemical Nuclear OrngeLCS1 500uL
An amphetamine whose physiological and toxicological properties are not known
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Cayman Chemical Tolperisone (hydrochloride), Purity: ≥98%, CAS: 3644-61-9, 250 mg
An inhibitor of voltage-gated sodium channels (IC50 = 198 µM for inhibition of peak sodium currents evoked by step depolarizations in DRG neurons in vitro); acts as an antispastic agent that attenuates monosynaptic, disynaptic, and polysynaptic reflux response to dorsal root stimulation in vivo
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Cayman Chemical Heneicosanoic Acid methyl ester, Purity: ≥98%, CAS: 6064-90-0, 250 mg
An ester form of heneicosanoic acid; has been used as an internal standard in the quantification of fatty acids in dairy products and fatty acid methyl esters in fish by GC-MS
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Cayman Chemical Trimethobenzamide (hydrochloride), Purity: ≥95%, CAS: 554-92-7, 100 mg
A D2 receptor antagonist and antiemetic; prevents apomorphine-induced emesis in dogs when administered at a dose of 20 mg/kg; stimulates contraction of isolated guinea pig ileum (ED50 = 8.7 μg/mL); decreases apomorphine-induced pecking responses in pigeons by 20% and increases the latent period of pecking from 4.3 to 8 minutes when used at a dose of 20 mg/kg; enhances compensation and decreases recovery time from 70 to 32 weeks in unilaterally labyrinthectomized cats, a model of vestibular injury, when administered at a dose of 6.7 g/kg per day for 2 weeks
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Cayman Chemical 9(Z),11(Z)-Conjugated Linoleic Acid, Purity: ≥96%, CAS: 544-70-7, 25 mg
An isomer of linoleic acid; has been found in milk from cows and other animals; cytotoxic to Caco-2 human colon cancer cells (EC50 = 446.1 µM) and induces changes in the miRNA profile
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Cayman Chemical Pipemidic Acid (hydrate), Purity: ≥98%, CAS: 72571-82-5, 1 g
An antibiotic; active against clinical isolates of E. coli, P. mirabilis, P. inconstans, Shigella, Salmonella, Alcaligenes, and V. parahaemolyticus (MICs = 0.78-100 µg/ml), as well as drug-resistant clinical isolates of E. coli, P. mirabilis, Klebsiella, and Shigella (MICs = 1.56-6.25 µg/ml); Protective against systemic S. aureus, E. coli, K. pneumoniae, and P. aeruginosa infections in mice (ED50s = 237.5, 204.1, 28.6, and 99.5 mg/kg, respectively); protective against P. aeruginosa-induced pulmonary and dermal infections (ED50s = 81.7 and 173.2 mg/kg, respectively), as well as E. coli, K. pneumoniae, and P. aeruginosa urinary bladder infections (ED50s = 4.8, 11.9, and 30.6 mg/kg, respectively), in mice
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Cayman Chemical Thioacetazone, Purity: ≥98%, CAS: 104-06-3, 500 mg
An antitubercular agent; active against M. tuberculosis H37Rv, M. kansasii Bostrom, and M. avium serotype 2 (MICs = 0.3, 0.6, and 20 µg/ml, respectively)
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Cayman Chemical Thiabendazole, Purity: ≥98%, CAS: 148-79-8, 50 g
A broad-spectrum anthelmintic active against a variety of helminths; kills greater than 95% of adult worms from ten genera; inhibits egg production and disrupts larval development; inhibits fumarate reductase in helminths, blocking energy production through the citric acid cycle; inhibits methionine aminopeptidase in E. coli (Ki = 40 nM; IC50 = 47.2 nM)
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Cayman Chemical C12 Galactosylceramide (d18:1/12:0), Purity: ≥95%, CAS: 41613-14-3, 50 mg
A bioactive sphingolipid; inhibits IL-4 production by 53.84% in EL4 T cells (10 μM); reduces the growth of human papillomavirus type 16-associated tumors in mice; reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus
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Cayman Chemical BODIPY 505/515, Purity: ≥98%, CAS: 21658-70-8, 500 mg
A fluorescent probe for lipid droplets; has been used for electron, epifluorescent, and confocal microscopy, as well as flow cytometry applications; has been used for live and fixed cell applications; ex/em = 505/515
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Cayman Chemical 1,2,3-Tri-13(Z)-Docosenoyl Glycerol, Purity: ≥95%, CAS: 2752-99-0, 100 mg
A triacylglycerol; has been found in nasturtium seed oil; dietary administration at 30% of fat calories in a 60% fat diet, in combination with sunflowerseed oil, induces severe cardiac lipidosis in rats after 1 week, with severity decreasing by 24 weeks; is a minor component of Lorenzo’s oil
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Cayman Chemical Metacetamol, Purity: ≥98%, CAS: 621-42-1, 500 g
A derivative of acetaminophen; not cytotoxic to isolated mouse hepatocytes (LC50 = >10 mM); induces necrosis and depletion of GSH in isolated human hepatocytes at 10 mM; does not induce hepatic necrosis in mice at 900 mg/kg
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Cayman Chemical IgG Fabmouse Monclonal n 50ug
Immunogen: Mouse IgG • Host: Goat • Species Reactivity: (+) Mouse • Cross Reactivity: (+) IgG1, IgG2a, IgG2b, IgG3; (-) Mouse IgM, IgA, IgE (-) Human, rabbit, rat IgG • Application: ELISA
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Cayman Chemical 5,7-Dihydroxy-4-methylcoumarin, Purity: ≥98%, CAS: 2107-76-8, 1 g
A synthetic coumarin with diverse biological activities; scavenges alkylperoxy radicals and HOCl (IC50 = 2.85 µM) in cell-free assays; inhibits lipid peroxidation in rat liver microsomes, A23187-induced TXB2 generation in isolated rat peritoneal leukocytes, and MPO activity in a cell-free assay (IC50s = 12, 1, and 1.06 µM, respectively); inhibits rat lens aldose reductase (IC50 = 17 µM); inhibits human CAI, CAIX, and CAXII (Kis = 8.4, 0.19, and 6.4 µM, respectively); inhibits arachidonic acid-induced platelet aggregation (IC50 = 45 µM); inhibits HCV NS5B polymerase (IC50 = 47.2 µM); active against H. pylori (MIC = 10 µg/ml)
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Cayman Chemical Galanin (2-11) amide (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt), Purity: ≥98%, 1 mg
A synthetic peptide fragment of galanin and an agonist of the GAL2 receptor (EC50 = 9.32 nM in a fluorescence imaging plate reader assay); selectively binds to the GAL2 receptor (IC50 = 1.76 nM for the rat receptor) over the GAL1 receptor (IC50 = 879 nM for the human receptor) but does also bind to the GAL3 receptor (Ki = 271 nM for the rat receptor); decreases immobility in the forced swim test in rats at 1 nmol/animal, i.c.v.; reduces the hind paw mechanical pain threshold and increases the hind paw cold sensitivity threshold in rats
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